Aberrantly expressed miR-582-3p maintains lung cancer stem cell-like traits by activating Wnt/β-catenin signalling

Cancer stem cells (CSCs) are involved in tumorigenesis, tumour recurrence and therapy resistance and Wnt signalling is essential for the development of the biological traits of CSCs. In non-small cell lung carcinoma (NSCLC), unlike in colon cancer, mutations in β-catenin and APC genes are uncommon;...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Fang, Lishan, Cai, Junchao, Chen, Baixue, Wu, Shanshan, Li, Rong, Xu, Xiaonan, Yang, Yi, Guan, Hongyu, Zhu, Xun, Zhang, Le, Yuan, Jie, Wu, Jueheng, Li, Mengfeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Pub. Group 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667703/
https://ncbi.nlm.nih.gov/pubmed/26468775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9640
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