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Aberrantly expressed miR-582-3p maintains lung cancer stem cell-like traits by activating Wnt/β-catenin signalling

Cancer stem cells (CSCs) are involved in tumorigenesis, tumour recurrence and therapy resistance and Wnt signalling is essential for the development of the biological traits of CSCs. In non-small cell lung carcinoma (NSCLC), unlike in colon cancer, mutations in β-catenin and APC genes are uncommon;...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Fang, Lishan, Cai, Junchao, Chen, Baixue, Wu, Shanshan, Li, Rong, Xu, Xiaonan, Yang, Yi, Guan, Hongyu, Zhu, Xun, Zhang, Le, Yuan, Jie, Wu, Jueheng, Li, Mengfeng
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Pub. Group 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667703/
https://ncbi.nlm.nih.gov/pubmed/26468775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9640
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