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Aberrantly expressed miR-582-3p maintains lung cancer stem cell-like traits by activating Wnt/β-catenin signalling

Cancer stem cells (CSCs) are involved in tumorigenesis, tumour recurrence and therapy resistance and Wnt signalling is essential for the development of the biological traits of CSCs. In non-small cell lung carcinoma (NSCLC), unlike in colon cancer, mutations in β-catenin and APC genes are uncommon;...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Fang, Lishan, Cai, Junchao, Chen, Baixue, Wu, Shanshan, Li, Rong, Xu, Xiaonan, Yang, Yi, Guan, Hongyu, Zhu, Xun, Zhang, Le, Yuan, Jie, Wu, Jueheng, Li, Mengfeng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667703/
https://ncbi.nlm.nih.gov/pubmed/26468775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9640
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