miR-17-92 fine-tunes MYC expression and function to ensure optimal B cell lymphoma growth

The synergism between c-MYC and miR-17-19b, a truncated version of the miR-17-92 cluster, is well-documented during tumor initiation. However, little is known about miR-17-19b function in established cancers. Here we investigate the role of miR-17-19b in c-MYC-driven lymphomas by integrating SILAC-b...

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Udgivet i:Nat Commun
Main Authors: Mihailovich, Marija, Bremang, Michael, Spadotto, Valeria, Musiani, Daniele, Vitale, Elena, Varano, Gabriele, Zambelli, Federico, Mancuso, Francesco M., Cairns, David A., Pavesi, Giulio, Casola, Stefano, Bonaldi, Tiziana
Format: Artigo
Sprog:Inglês
Udgivet: Nature Pub. Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667639/
https://ncbi.nlm.nih.gov/pubmed/26555894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9725
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