Functional classification of memory CD8(+) T cells by CX(3)CR1 expression

Localization of memory CD8(+) T cells to lymphoid or peripheral tissues is believed to correlate with proliferative capacity or effector function. Here we demonstrate that the fractalkine-receptor/CX(3)CR1 distinguishes memory CD8(+) T cells with cytotoxic effector function from those with prolifera...

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Pubblicato in:Nat Commun
Autori principali: Böttcher, Jan P., Beyer, Marc, Meissner, Felix, Abdullah, Zeinab, Sander, Jil, Höchst, Bastian, Eickhoff, Sarah, Rieckmann, Jan C., Russo, Caroline, Bauer, Tanja, Flecken, Tobias, Giesen, Dominik, Engel, Daniel, Jung, Steffen, Busch, Dirk H., Protzer, Ulrike, Thimme, Robert, Mann, Matthias, Kurts, Christian, Schultze, Joachim L., Kastenmüller, Wolfgang, Knolle, Percy A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Pub. Group 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667439/
https://ncbi.nlm.nih.gov/pubmed/26404698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9306
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