Functional classification of memory CD8(+) T cells by CX(3)CR1 expression

Localization of memory CD8(+) T cells to lymphoid or peripheral tissues is believed to correlate with proliferative capacity or effector function. Here we demonstrate that the fractalkine-receptor/CX(3)CR1 distinguishes memory CD8(+) T cells with cytotoxic effector function from those with prolifera...

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Publicat a:Nat Commun
Autors principals: Böttcher, Jan P., Beyer, Marc, Meissner, Felix, Abdullah, Zeinab, Sander, Jil, Höchst, Bastian, Eickhoff, Sarah, Rieckmann, Jan C., Russo, Caroline, Bauer, Tanja, Flecken, Tobias, Giesen, Dominik, Engel, Daniel, Jung, Steffen, Busch, Dirk H., Protzer, Ulrike, Thimme, Robert, Mann, Matthias, Kurts, Christian, Schultze, Joachim L., Kastenmüller, Wolfgang, Knolle, Percy A.
Format: Artigo
Idioma:Inglês
Publicat: Nature Pub. Group 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667439/
https://ncbi.nlm.nih.gov/pubmed/26404698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9306
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