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Exclusive CX(3)CR1 dependence of kidney DCs impacts glomerulonephritis progression
DCs and macrophages both express the chemokine receptor CX(3)CR1. Here we demonstrate that its ligand, CX(3)CL1, is highly expressed in the murine kidney and intestine. CX(3)CR1 deficiency markedly reduced DC numbers in the healthy and inflamed kidney cortex, and to a lesser degree in the kidney med...
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| Hoofdauteurs: | , , , , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Clinical Investigation
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3784547/ https://ncbi.nlm.nih.gov/pubmed/23999431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI70143 |
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