Exclusive CX(3)CR1 dependence of kidney DCs impacts glomerulonephritis progression

DCs and macrophages both express the chemokine receptor CX(3)CR1. Here we demonstrate that its ligand, CX(3)CL1, is highly expressed in the murine kidney and intestine. CX(3)CR1 deficiency markedly reduced DC numbers in the healthy and inflamed kidney cortex, and to a lesser degree in the kidney med...

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Main Authors: Hochheiser, Katharina, Heuser, Christoph, Krause, Torsten A., Teteris, Simon, Ilias, Anissa, Weisheit, Christina, Hoss, Florian, Tittel, André P., Knolle, Percy A., Panzer, Ulf, Engel, Daniel R., Tharaux, Pierre-Louis, Kurts, Christian
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2013
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784547/
https://ncbi.nlm.nih.gov/pubmed/23999431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI70143
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