Exclusive CX(3)CR1 dependence of kidney DCs impacts glomerulonephritis progression

DCs and macrophages both express the chemokine receptor CX(3)CR1. Here we demonstrate that its ligand, CX(3)CL1, is highly expressed in the murine kidney and intestine. CX(3)CR1 deficiency markedly reduced DC numbers in the healthy and inflamed kidney cortex, and to a lesser degree in the kidney med...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hochheiser, Katharina, Heuser, Christoph, Krause, Torsten A., Teteris, Simon, Ilias, Anissa, Weisheit, Christina, Hoss, Florian, Tittel, André P., Knolle, Percy A., Panzer, Ulf, Engel, Daniel R., Tharaux, Pierre-Louis, Kurts, Christian
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784547/
https://ncbi.nlm.nih.gov/pubmed/23999431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI70143
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