Oppositional COMT Val158Met effects on resting state functional connectivity in adolescents and adults

Prefrontal dopamine levels are relatively increased in adolescence compared to adulthood. Genetic variation of COMT (COMT Val158Met) results in lower enzymatic activity and higher dopamine availability in Met carriers. Given the dramatic changes of synaptic dopamine during adolescence, it has been s...

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Bibliografski detalji
Izdano u:Brain Struct Funct
Glavni autori: Meyer, Bernhard M., Huemer, Julia, Rabl, Ulrich, Boubela, Roland N., Kalcher, Klaudius, Berger, Andreas, Banaschewski, Tobias, Barker, Gareth, Bokde, Arun, Büchel, Christian, Conrod, Patricia, Desrivières, Sylvane, Flor, Herta, Frouin, Vincent, Gallinat, Jurgen, Garavan, Hugh, Heinz, Andreas, Ittermann, Bernd, Jia, Tianye, Lathrop, Mark, Martinot, Jean-Luc, Nees, Frauke, Rietschel, Marcella, Smolka, Michael N., Bartova, Lucie, Popovic, Ana, Scharinger, Christian, Sitte, Harald H., Steiner, Hans, Friedrich, Max H., Kasper, Siegfried, Perkmann, Thomas, Praschak-Rieder, Nicole, Haslacher, Helmuth, Esterbauer, Harald, Moser, Ewald, Schumann, Gunter, Pezawas, Lukas
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2014
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667398/
https://ncbi.nlm.nih.gov/pubmed/25319752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00429-014-0895-5
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