Oppositional COMT Val158Met effects on resting state functional connectivity in adolescents and adults

Prefrontal dopamine levels are relatively increased in adolescence compared to adulthood. Genetic variation of COMT (COMT Val158Met) results in lower enzymatic activity and higher dopamine availability in Met carriers. Given the dramatic changes of synaptic dopamine during adolescence, it has been s...

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Detalhes bibliográficos
Publicado no:Brain Struct Funct
Main Authors: Meyer, Bernhard M., Huemer, Julia, Rabl, Ulrich, Boubela, Roland N., Kalcher, Klaudius, Berger, Andreas, Banaschewski, Tobias, Barker, Gareth, Bokde, Arun, Büchel, Christian, Conrod, Patricia, Desrivières, Sylvane, Flor, Herta, Frouin, Vincent, Gallinat, Jurgen, Garavan, Hugh, Heinz, Andreas, Ittermann, Bernd, Jia, Tianye, Lathrop, Mark, Martinot, Jean-Luc, Nees, Frauke, Rietschel, Marcella, Smolka, Michael N., Bartova, Lucie, Popovic, Ana, Scharinger, Christian, Sitte, Harald H., Steiner, Hans, Friedrich, Max H., Kasper, Siegfried, Perkmann, Thomas, Praschak-Rieder, Nicole, Haslacher, Helmuth, Esterbauer, Harald, Moser, Ewald, Schumann, Gunter, Pezawas, Lukas
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667398/
https://ncbi.nlm.nih.gov/pubmed/25319752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00429-014-0895-5
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