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Small-angle scattering determination of the shape and localization of human cytochrome P450 embedded in a phospholipid nanodisc environment

Membrane proteins reconstituted into phospholipid nanodiscs comprise a soluble entity accessible to solution small-angle X-ray scattering (SAXS) studies. It is demonstrated that using SAXS data it is possible to determine both the shape and localization of the membrane protein cytochrome P450 3A4 (C...

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Bibliografske podrobnosti
izdano v:Acta Crystallogr D Biol Crystallogr
Main Authors: Skar-Gislinge, Nicholas, Kynde, Søren A. R., Denisov, Ilia G., Ye, Xin, Lenov, Ivan, Sligar, Stephen G., Arleth, Lise
Format: Artigo
Jezik:Inglês
Izdano: International Union of Crystallography 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667284/
https://ncbi.nlm.nih.gov/pubmed/26627649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004715018702
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