Mycobacterium tuberculosis Infection Induces HDAC1-Mediated Suppression of IL-12B Gene Expression in Macrophages

Downregulation of host gene expression is one of the many strategies employed by intracellular pathogens such as Mycobacterium tuberculosis (MTB) to survive inside the macrophages and cause disease. The underlying molecular mechanism behind the downregulation of host defense gene expression is large...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Chandran, Aneesh, Antony, Cecil, Jose, Leny, Mundayoor, Sathish, Natarajan, Krishnamurthy, Kumar, R. Ajay
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667035/
https://ncbi.nlm.nih.gov/pubmed/26697414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2015.00090
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