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AMP-activated protein kinase inhibits transforming growth factor-β-mediated vascular smooth muscle cell growth: implications for a Smad-3-dependent mechanism

Dysfunctional vascular growth is a major contributor to cardiovascular disease, the leading cause of morbidity and mortality worldwide. Growth factor-induced activation of vascular smooth muscle cells (VSMCs) results in a phenotypic switch from a quiescent, contractile state to a proliferative state...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Physiol Heart Circ Physiol
Prif Awduron: Stone, Joshua D., Holt, Andrew W., Vuncannon, Jackson R., Brault, Jeffrey J., Tulis, David A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666965/
https://ncbi.nlm.nih.gov/pubmed/26276823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00846.2014
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