IRON REGULATORY PROTEINS MEDIATE HOST RESISTANCE TO SALMONELLA INFECTION

Macrophages are essential for systemic iron recycling, and also control iron availability to pathogens. Iron metabolism in mammalian cells is orchestrated post-transcriptionally by iron-regulatory proteins (IRP)-1 and -2. Here, we generated mice with selective and combined ablation of both IRPs in m...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Nairz, Manfred, Ferring-Appel, Dunja, Casarrubea, Daniela, Sonnweber, Thomas, Viatte, Lydie, Schroll, Andrea, Haschka, David, Fang, Ferric C., Hentze, Matthias W., Weiss, Guenter, Galy, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666941/
https://ncbi.nlm.nih.gov/pubmed/26190773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2015.06.017
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