Nifedipine Affects the Course of Salmonella enterica Serovar Typhimurium Infection by Modulating Macrophage Iron Homeostasis

Background. Iron overload can adversely influence the course of infection by increasing microbial replication and suppressing antimicrobial immune effector pathways. Recently, we have shown that the calcium channel blocker nifedipine can mobilize tissue iron in mouse models of iron overload. We ther...

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Hlavní autoři: Mair, Sabine M., Nairz, Manfred, Bellmann-Weiler, Rosa, Muehlbacher, Thomas, Schroll, Andrea, Theurl, Igor, Moser, Patrizia L., Talasz, Heribert, Fang, Ferric C., Weiss, Guenter
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
Major Articles and Brief Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156106/
https://ncbi.nlm.nih.gov/pubmed/21844295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir395
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