Blockade of CD40 ligand for intercellular communication reduces hypertension, placental oxidative stress, and AT(1)-AA in response to adoptive transfer of CD4(+) T lymphocytes from RUPP rats

Preeclampsia (PE) is associated with altered immune activation during pregnancy. We have previously shown that adoptive transfer of CD4(+) T cells from the reduced uterine perfusion pressure (RUPP) rat model of PE increases blood pressure, oxidative stress (ROS), and inflammation in normal pregnant...

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Detalhes bibliográficos
Publicado no:Am J Physiol Regul Integr Comp Physiol
Main Authors: Cornelius, Denise C., Castillo, Javier, Porter, Justin, Amaral, Lorena M., Campbell, Nathan, Paige, Adrienne, Thomas, Alexia J., Harmon, Ashlyn, Cunningham, Mark W., Wallace, Kedra, Herse, Florian, Wallukat, Gerd, Dechend, Ralf, LaMarca, Babbette
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Fluid and Electrolyte Homeostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666934/
https://ncbi.nlm.nih.gov/pubmed/26310940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00273.2015
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