Blockade of CD40 ligand for intercellular communication reduces hypertension, placental oxidative stress, and AT(1)-AA in response to adoptive transfer of CD4(+) T lymphocytes from RUPP rats

Preeclampsia (PE) is associated with altered immune activation during pregnancy. We have previously shown that adoptive transfer of CD4(+) T cells from the reduced uterine perfusion pressure (RUPP) rat model of PE increases blood pressure, oxidative stress (ROS), and inflammation in normal pregnant...

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Veröffentlicht in:Am J Physiol Regul Integr Comp Physiol
Hauptverfasser: Cornelius, Denise C., Castillo, Javier, Porter, Justin, Amaral, Lorena M., Campbell, Nathan, Paige, Adrienne, Thomas, Alexia J., Harmon, Ashlyn, Cunningham, Mark W., Wallace, Kedra, Herse, Florian, Wallukat, Gerd, Dechend, Ralf, LaMarca, Babbette
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2015
Schlagworte:
Fluid and Electrolyte Homeostasis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666934/
https://ncbi.nlm.nih.gov/pubmed/26310940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00273.2015
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