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Blockade of CD40 ligand for intercellular communication reduces hypertension, placental oxidative stress, and AT(1)-AA in response to adoptive transfer of CD4(+) T lymphocytes from RUPP rats

Preeclampsia (PE) is associated with altered immune activation during pregnancy. We have previously shown that adoptive transfer of CD4(+) T cells from the reduced uterine perfusion pressure (RUPP) rat model of PE increases blood pressure, oxidative stress (ROS), and inflammation in normal pregnant...

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Publicat a:Am J Physiol Regul Integr Comp Physiol
Autors principals: Cornelius, Denise C., Castillo, Javier, Porter, Justin, Amaral, Lorena M., Campbell, Nathan, Paige, Adrienne, Thomas, Alexia J., Harmon, Ashlyn, Cunningham, Mark W., Wallace, Kedra, Herse, Florian, Wallukat, Gerd, Dechend, Ralf, LaMarca, Babbette
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666934/
https://ncbi.nlm.nih.gov/pubmed/26310940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00273.2015
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