ER Chaperone BiP/GRP78 Is Required for Myelinating Cell Survival and Provides Protection during Experimental Autoimmune Encephalomyelitis

Myelinating cells synthesize large amounts of membrane protein through the secretory pathway, which makes these cells particularly sensitive to perturbations of the endoplasmic reticulum (ER). Ig binding protein (BiP), also known as glucose-regulated protein 78 (GRP78), is a critical ER chaperone th...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Hussien, Yassir, Podojil, Joseph R., Robinson, Andrew P., Lee, Amy S., Miller, Steven D., Popko, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666917/
https://ncbi.nlm.nih.gov/pubmed/26631473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0693-15.2015
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