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Large-scale identification of sequence variants impacting human transcription factor occupancy in vivo

The function of human regulatory regions depends exquisitely on their local genomic environment and cellular context, complicating experimental analysis of the expanding pool of common disease- and trait-associated variants that localize within regulatory DNA. We leverage allelically resolved genomi...

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Publicat a:Nat Genet
Autors principals: Maurano, Matthew T., Haugen, Eric, Sandstrom, Richard, Vierstra, Jeff, Shafer, Anthony, Kaul, Rajinder, Stamatoyannopoulos, John A.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666772/
https://ncbi.nlm.nih.gov/pubmed/26502339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3432
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