Simian virus 40 large tumor antigen-immortalized normal human liver epithelial cells express hepatocyte characteristics and metabolize chemical carcinogens.

Normal human liver tissue and cultured human hepatocytes are valuable models to study xenobiotic metabolism and toxicity, but they only have a limited in vitro life-span and are not readily available. This report describes the establishment of replicative cultures of human adult liver epithelial cel...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Pfeifer, A M, Cole, K E, Smoot, D T, Weston, A, Groopman, J D, Shields, P G, Vignaud, J M, Juillerat, M, Lipsky, M M, Trump, B F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46667/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7685115/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.11.5123
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