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Regulation of α4β2α5 nicotinic acetylcholinergic receptors in rat cerebral cortex in early and late adolescence: sex differences in response to chronic nicotine

Chronic nicotine administration in animals, and smoking in humans, causes up-regulation of α4β2* neuronal nicotinic receptors (nAChRs), which has been hypothesized to contribute to the addictive actions of nicotine. We used a rat model to test whether such up-regulatory effects differ in adolescents...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: Hoegberg, Bethany G., Lomazzo, Ermelinda, Lee, Norman H., Perry, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666496/
https://ncbi.nlm.nih.gov/pubmed/26272110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.08.015
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