Persistent β(2)*-Nicotinic Acetylcholinergic Receptor Dysfunction in Major Depressive Disorder

BACKGROUND: Modulation of nicotinic acetylcholine receptors (nAChRs), specifically α(4)β(2) subunit containing nAChRs, may be effective in the treatment of patients with major depressive disorder (MDD). Using [(123)I] 5-I-A-85380 single photon emission computed tomography (SPECT), we studied β(2) su...

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Detalhes bibliográficos
Main Authors: Saricicek, Aybala, Esterlis, Irina, Maloney, Kathleen H., Mineur, Yann S., Ruf, Barbara M., Muralidharan, Anjana, Chen, Jason I., Cosgrove, Kelly P., Kerestes, Rebecca, Ghose, Subroto, Tamminga, Carol A., Pittman, Brian, Bois, Frederic, Tamagnan, Gilles, Seibyl, John, Picciotto, Marina R., Staley, Julie K., Bhagwagar, Zubin
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494404/
https://ncbi.nlm.nih.gov/pubmed/22772158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1176/appi.ajp.2012.11101546
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