Transcriptional Up-Regulation of APE1/Ref-1 in Hepatic Tumor: Role in Hepatocytes Resistance to Oxidative Stress and Apoptosis

OBJECTIVE: Human Hepatocellular Carcinoma (HCC) is the fifth most frequent neoplasm worldwide and the most serious complication of long-standing chronic liver diseases (CLD). Its development is associated with chronic inflammation and sustained oxidative stress. Deregulation of apurinic apyrimidinic...

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Publicado en:PLoS One
Autores principales: Di Maso, Vittorio, Mediavilla, María Gabriela, Vascotto, Carlo, Lupo, Francesco, Baccarani, Umberto, Avellini, Claudio, Tell, Gianluca, Tiribelli, Claudio, Crocè, Lory Saveria
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666459/
https://ncbi.nlm.nih.gov/pubmed/26624999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143289
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