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The current state of eukaryotic DNA base damage and repair

DNA damage is a natural hazard of life. The most common DNA lesions are base, sugar, and single-strand break damage resulting from oxidation, alkylation, deamination, and spontaneous hydrolysis. If left unrepaired, such lesions can become fixed in the genome as permanent mutations. Thus, evolution h...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Bauer, Nicholas C., Corbett, Anita H., Doetsch, Paul W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666366/
https://ncbi.nlm.nih.gov/pubmed/26519467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1136
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