Collaborator of alternative reading frame protein (CARF) regulates early processing of pre-ribosomal RNA by retaining XRN2 (5′-3′ exoribonuclease) in the nucleoplasm

Collaborator of alternative reading frame protein (CARF) associates directly with ARF, p53, and/or human double minute 2 protein (HDM2), a ubiquitin-protein ligase, without cofactors and regulates cell proliferation by forming a negative feedback loop. Although ARF, p53, and HDM2 also participate in...

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Foilsithe in:Nucleic Acids Res
Main Authors: Sato, Shigeko, Ishikawa, Hideaki, Yoshikawa, Harunori, Izumikawa, Keiichi, Simpson, Richard J., Takahashi, Nobuhiro
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2015
Ábhair:
Nucleic Acid Enzymes
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666357/
https://ncbi.nlm.nih.gov/pubmed/26531822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1069
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