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The role of B-cell receptor inhibitors in the treatment of patients with chronic lymphocytic leukemia
Chronic lymphocytic leukemia is a malignancy of mature auto-reactive B cells. Genetic and functional studies implicate B-cell receptor signaling as a pivotal pathway in its pathogenesis. Full B-cell receptor activation requires tumor-microenvironment interactions in lymphoid tissues. Spleen tyrosine...
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| 出版年: | Haematologica |
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| 第一著者: | |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Ferrata Storti Foundation
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4666325/ https://ncbi.nlm.nih.gov/pubmed/26628631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2014.119123 |
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