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Formulation Development of Spherical Crystal Agglomerates of Itraconazole for Preparation of Directly Compressible Tablets with Enhanced Bioavailability

The objective of the present work was to formulate tablet dosage form of itraconazole with enhanced bioavailability. Spherical crystal agglomerates (SCA) of itraconazole prepared by quasi emulsification solvent diffusion method using Soluplus and polyethylene glycol 4000 (PEG 4000) showed increased...

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書誌詳細
出版年:AAPS PharmSciTech
主要な著者: Fadke, Janki, Desai, Jagruti, Thakkar, Hetal
フォーマット: Artigo
言語:Inglês
出版事項: Springer US 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666265/
https://ncbi.nlm.nih.gov/pubmed/25991065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-015-0332-y
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