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Formulation Development of Spherical Crystal Agglomerates of Itraconazole for Preparation of Directly Compressible Tablets with Enhanced Bioavailability

The objective of the present work was to formulate tablet dosage form of itraconazole with enhanced bioavailability. Spherical crystal agglomerates (SCA) of itraconazole prepared by quasi emulsification solvent diffusion method using Soluplus and polyethylene glycol 4000 (PEG 4000) showed increased...

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Detalhes bibliográficos
Publicado no:AAPS PharmSciTech
Main Authors: Fadke, Janki, Desai, Jagruti, Thakkar, Hetal
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666265/
https://ncbi.nlm.nih.gov/pubmed/25991065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-015-0332-y
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