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Formulation Development of Spherical Crystal Agglomerates of Itraconazole for Preparation of Directly Compressible Tablets with Enhanced Bioavailability

The objective of the present work was to formulate tablet dosage form of itraconazole with enhanced bioavailability. Spherical crystal agglomerates (SCA) of itraconazole prepared by quasi emulsification solvent diffusion method using Soluplus and polyethylene glycol 4000 (PEG 4000) showed increased...

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Dettagli Bibliografici
Pubblicato in:AAPS PharmSciTech
Autori principali: Fadke, Janki, Desai, Jagruti, Thakkar, Hetal
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666265/
https://ncbi.nlm.nih.gov/pubmed/25991065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-015-0332-y
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