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The mitochondrial fission receptor Mff selectively recruits oligomerized Drp1

Dynamin-related protein 1 (Drp1) is the GTP-hydrolyzing mechanoenzyme that catalyzes mitochondrial fission in the cell. Residing in the cytosol as dimers and tetramers, Drp1 is recruited by receptors on the mitochondrial outer membrane, where it further assembles into a helical ring that drives divi...

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Bibliographic Details
Published in:Mol Biol Cell
Main Authors: Liu, Raymond, Chan, David C.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666140/
https://ncbi.nlm.nih.gov/pubmed/26446846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-08-0591
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