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Crystal structure and functional analysis of MiD49, a receptor for the mitochondrial fission protein Drp1

Mitochondrial fission requires recruitment of dynamin-related protein 1 (Drp1) to the mitochondrial surface, where assembly leads to activation of its GTP-dependent scission function. MiD49 and MiD51 are two receptors on the mitochondrial outer membrane that can recruit Drp1 to facilitate mitochondr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Protein Sci
Hauptverfasser: Losón, Oliver C, Meng, Shuxia, Ngo, Huu, Liu, Raymond, Kaiser, Jens T, Chan, David C
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353364/
https://ncbi.nlm.nih.gov/pubmed/25581164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2629
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