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The C-terminal CGHC motif of protein disulfide isomerase supports thrombosis
Protein disulfide isomerase (PDI) has two distinct CGHC redox-active sites; however, the contribution of these sites during different physiologic reactions, including thrombosis, is unknown. Here, we evaluated the role of PDI and redox-active sites of PDI in thrombosis by generating mice with blood...
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Publicado no: | J Clin Invest |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4665788/ https://ncbi.nlm.nih.gov/pubmed/26529254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80319 |
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