The C-terminal CGHC motif of protein disulfide isomerase supports thrombosis

Protein disulfide isomerase (PDI) has two distinct CGHC redox-active sites; however, the contribution of these sites during different physiologic reactions, including thrombosis, is unknown. Here, we evaluated the role of PDI and redox-active sites of PDI in thrombosis by generating mice with blood...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Zhou, Junsong, Wu, Yi, Wang, Lu, Rauova, Lubica, Hayes, Vincent M., Poncz, Mortimer, Essex, David W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665788/
https://ncbi.nlm.nih.gov/pubmed/26529254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80319
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