Platelet-derived HMGB1 is a critical mediator of thrombosis

Thrombosis and inflammation are intricately linked in several major clinical disorders, including disseminated intravascular coagulation and acute ischemic events. The damage-associated molecular pattern molecule high-mobility group box 1 (HMGB1) is upregulated by activated platelets in multiple inf...

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Bibliografski detalji
Izdano u:J Clin Invest
Glavni autori: Vogel, Sebastian, Bodenstein, Rebecca, Chen, Qiwei, Feil, Susanne, Feil, Robert, Rheinlaender, Johannes, Schäffer, Tilman E., Bohn, Erwin, Frick, Julia-Stefanie, Borst, Oliver, Münzer, Patrick, Walker, Britta, Markel, Justin, Csanyi, Gabor, Pagano, Patrick J., Loughran, Patricia, Jessup, Morgan E., Watkins, Simon C., Bullock, Grant C., Sperry, Jason L., Zuckerbraun, Brian S., Billiar, Timothy R., Lotze, Michael T., Gawaz, Meinrad, Neal, Matthew D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2015
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665785/
https://ncbi.nlm.nih.gov/pubmed/26551681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI81660
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