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Circulating HMGB1 and RAGE as Clinical Biomarkers in Malignant and Autoimmune Diseases

High molecular group box 1 (HMGB1) is a highly conserved member of the HMG-box-family; abundantly expressed in almost all human cells and released in apoptosis; necrosis or by activated immune cells. Once in the extracellular space, HMGB1 can act as a danger associated molecular pattern (DAMP), thus...

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Detalles Bibliográficos
Publicado en:Diagnostics (Basel)
Main Authors: Pilzweger, Christin, Holdenrieder, Stefan
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665591/
https://ncbi.nlm.nih.gov/pubmed/26854151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/diagnostics5020219
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