Critical role of RAGE and HMGB1 in inflammatory heart disease

Autoimmune response to cardiac troponin I (TnI) induces inflammation and fibrosis in the myocardium. High-mobility group box 1 (HMGB1) is a multifunctional protein that exerts proinflammatory activity by mainly binding to receptor for advanced glycation end products (RAGE). The involvement of the HM...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Bangert, Anna, Andrassy, Martin, Müller, Anna-Maria, Bockstahler, Mariella, Fischer, Andrea, Volz, Christian H., Leib, Christoph, Göser, Stefan, Korkmaz-Icöz, Sevil, Zittrich, Stefan, Jungmann, Andreas, Lasitschka, Felix, Pfitzer, Gabriele, Müller, Oliver J., Katus, Hugo A., Kaya, Ziya
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720305/
https://ncbi.nlm.nih.gov/pubmed/26715748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522288113
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