A Comparative Analysis of Synthetic Quorum Sensing Modulators in Pseudomonas aeruginosa: New Insights into Mechanism, Active Efflux Susceptibility, Phenotypic Response, and Next-Generation Ligand Design

[Image: see text] Quorum sensing (QS) is a chemical signaling mechanism that allows bacterial populations to coordinate gene expression in response to social and environmental cues. Many bacterial pathogens use QS to initiate infection at high cell densities. Over the past two decades, chemical anta...

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Bibliographic Details
Published in:J Am Chem Soc
Main Authors: Moore, Joseph D., Rossi, Francis M., Welsh, Michael A., Nyffeler, Kayleigh E., Blackwell, Helen E.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2015
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665086/
https://ncbi.nlm.nih.gov/pubmed/26491787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b06728
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