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Side Chain Conformational Distributions of a Small Protein Derived from Model-Free Analysis of a Large Set of Residual Dipolar Couplings

[Image: see text] Accurate quantitative measurement of structural dispersion in proteins remains a prime challenge to both X-ray crystallography and NMR spectroscopy. Here we use a model-free approach based on measurement of many residual dipolar couplings (RDCs) in differentially orienting aqueous...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Li, Fang, Grishaev, Alexander, Ying, Jinfa, Bax, Ad
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2015
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665082/
https://ncbi.nlm.nih.gov/pubmed/26523828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b10072
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