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Accurate Measurement of Residual Dipolar Couplings in Large RNAs by Variable Flip Angle NMR

NMR approaches using nucleotide-specific deuterium labeling schemes have enabled structural studies of biologically relevant RNAs of increasing size and complexity. Although local structure is well-determined using these methods, definition of global structural features, including relative orientati...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Marchant, Jan, Bax, Ad, Summers, Michael F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021016/
https://ncbi.nlm.nih.gov/pubmed/29757635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b03298
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