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Fisetin and luteolin protect human retinal pigment epithelial cells from oxidative stress-induced cell death and regulate inflammation

Degeneration of retinal pigment epithelial (RPE) cells is a clinical hallmark of age-related macular degeneration (AMD), the leading cause of blindness among aged people in the Western world. Both inflammation and oxidative stress are known to play vital roles in the development of this disease. Her...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Hytti, Maria, Piippo, Niina, Korhonen, Eveliina, Honkakoski, Paavo, Kaarniranta, Kai, Kauppinen, Anu
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664957/
https://ncbi.nlm.nih.gov/pubmed/26619957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17645
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