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Within patient microevolution of Mycobacterium tuberculosis correlates with heterogeneous responses to treatment

Genetic heterogeneity of Mycobacterium tuberculosis (MTB) within a patient has caused great concern as it might complicate antibiotic treatment and cause treatment failure. But the extent of genetic heterogeneity has not been described in detail nor has its association with heterogeneous treatment r...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Liu, Qingyun, Via, Laura E., Luo, Tao, Liang, Lili, Liu, Xin, Wu, Sufang, Shen, Qingyu, Wei, Wang, Ruan, Xianglin, Yuan, Xing, Zhang, Guolong, Barry, Clifton E., Gao, Qian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664930/
https://ncbi.nlm.nih.gov/pubmed/26620446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17507
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