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Biomarkers in phase I–II chemoprevention trials: lessons from the NCI experience

Early phase clinical trials are an essential component of chemopreventive drug development to identify signals of drug efficacy that can subsequently be explored definitively in phase III trials. Whereas phase I trials focus on safety and identification of optimal dose and schedule for cancer preven...

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Detalhes bibliográficos
Publicado no:Ecancermedicalscience
Autor principal: Szabo, Eva
Formato: Artigo
Idioma:Inglês
Publicado em: Cancer Intelligence 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664504/
https://ncbi.nlm.nih.gov/pubmed/26635903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3332/ecancer.2015.599
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