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Enhanced Diastereoselectivity in β-Mannopyranosylation through the Use of Sterically Minimal Propargyl Ether Protecting Groups

2-O-Propargyl ethers are shown to be advantageous in the 4,6-O-benzylidene acetal directed β-mannosylation reaction. The effect is most pronounced when the 3-O-protecting group is bulky silyl ether or a glycosidic bond, however, even with a 3-O-benzyl ether the use of a 2-O-propargyl ether results i...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Crich, David, Jayalath, Prasanna, Hutton, Thomas K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664462/
https://ncbi.nlm.nih.gov/pubmed/16599600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo0526789
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