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Mapping Soluble Guanylyl Cyclase and Protein Disulfide Isomerase Regions of Interaction

Soluble guanylyl cyclase (sGC) is a heterodimeric nitric oxide (NO) receptor that produces cyclic GMP. This signaling mechanism is a key component in the cardiovascular system. NO binds to heme in the β subunit and stimulates the catalytic conversion of GTP to cGMP several hundred fold. Several endo...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Heckler, Erin J., Kholodovych, Vladyslav, Jain, Mohit, Liu, Tong, Li, Hong, Beuve, Annie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664405/
https://ncbi.nlm.nih.gov/pubmed/26618351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143523
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