Hypoxia is associated with a lower expression of genes involved in lipogenesis in visceral adipose tissue

BACKGROUND: A key role for HIF-1α in the promotion and maintenance of dietary obesity has been proposed. We analyzed the association between hypoxia and de novo lipogenesis in human adipose tissue. METHODS: We studied HIF-1α mRNA and protein expression in fasting status in visceral adipose tissue (V...

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Udgivet i:J Transl Med
Main Authors: García-Fuentes, Eduardo, Santiago-Fernández, Concepción, Gutiérrez-Repiso, Carolina, Mayas, María D., Oliva-Olivera, Wilfredo, Coín-Aragüez, Leticia, Alcaide, Juan, Ocaña-Wilhelmi, Luis, Vendrell, Joan, Tinahones, Francisco J., Garrido-Sánchez, Lourdes
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4663723/
https://ncbi.nlm.nih.gov/pubmed/26619907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0732-5
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