Progression from High Insulin Resistance to Type 2 Diabetes Does Not Entail Additional Visceral Adipose Tissue Inflammation

Obesity is associated with a low-grade chronic inflammation state. As a consequence, adipose tissue expresses pro-inflammatory cytokines that propagate inflammatory responses systemically elsewhere, promoting whole-body insulin resistance and consequential islet β-cell exhaustation. Thus, insulin re...

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Autori principali: Barbarroja, Nuria, Lopez-Pedrera, Chary, Garrido-Sanchez, Lourdes, Mayas, Maria Dolores, Oliva-Olivera, Wilfredo, Bernal-Lopez, Maria Rosa, El Bekay, Rajaa, Tinahones, Francisco Jose
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480488/
https://ncbi.nlm.nih.gov/pubmed/23110196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048155
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