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Disturbed T Cell Signaling and Altered Th17 and Regulatory T Cell Subsets in the Pathogenesis of Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the presence of autoantibodies against nuclear components. Circulating immune complexes of chromatin and autoantibodies deposit in various tissues leading to inflammation and tissue damage. It has been well documented that...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Rother, Nils, van der Vlag, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4663269/
https://ncbi.nlm.nih.gov/pubmed/26648939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00610
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