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Disturbed T cell signaling and altered Th17 and regulatory T cell subsets in the pathogenesis of systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the presence of autoantibodies against nuclear components. Circulating immune complexes of chromatin and autoantibodies deposit in various tissues leading to inflammation and tissue damage. It has been well documented that...

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Detalhes bibliográficos
Main Authors: Nils eRother, Johan eVan Der Vlag
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015-11-01
Colecção:Frontiers in Immunology
Assuntos:
Acesso em linha:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00610/full
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