Epigenetic screening of salivary gland mucoepidermoid carcinoma identifies hypomethylation of CLIC3 as a common alteration

OBJECTIVES: The role of promoter methylation in the development of mucoepidermoid carcinoma (MEC) has not been fully explored. In this study, we investigated the epigenetic landscape of MEC. METHODS: The Illumina HumanMethylation27 BeadChip array and differential methylation analysis were utilized t...

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Bibliografske podrobnosti
izdano v:Oral Oncol
Main Authors: Wang, Zhiming, Ling, Shizhang, Rettig, Eleni, Sobel, Ryan, Tan, Marietta, Fertig, Elana J., Considine, Michael, El-Naggar, Adel K., Brait, Mariana, Fakhry, Carole, Ha, Patrick K.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4663116/
https://ncbi.nlm.nih.gov/pubmed/26490796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2015.09.010
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