EMT is not required for lung metastasis but contributes to chemoresistance

The role of epithelial to mesenchymal transition (EMT) in metastasis is a longstanding source of controversy, largely due to an inability to monitor transient and reversible EMT phenotypes in vivo. We established an EMT lineage tracing system to monitor this process, using a mesenchymal-specific Cre...

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發表在:Nature
Main Authors: Fischer, Kari R., Durrans, Anna, Lee, Sharrell, Sheng, Jianting, Li, Fuhai, Wong, Stephen, Choi, Hyejin, El Rayes, Tina, Ryu, Seongho, Troeger, Juliane, Schwabe, Robert F., Vahdat, Linda T., Altorki, Nasser K., Mittal, Vivek, Gao, Dingcheng
格式: Artigo
語言:Inglês
出版: 2015
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662610/
https://ncbi.nlm.nih.gov/pubmed/26560033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature15748
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