Tracking sub-clonal TP53 mutated tumor cells in human metastatic renal cell carcinoma

Renal Cell Carcinomas (RCCs) are heterogeneous tumors with late acquisition of TP53 abnormalities during their evolution. They harbor TP53 abnormalities in their metastases. We aimed to study TP53 gene alterations in tissue samples from primary and metastatic RCCs in 36 patients followed up over a m...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Bousquet, Guilhem, Bouchtaoui, Morad El, Leboeuf, Christophe, Battistella, Maxime, Varna, Mariana, Ferreira, Irmine, Plassa, Louis-François, Hamdan, Diaddin, Bertheau, Philippe, Feugeas, Jean-Paul, Damotte, Diane, Janin, Anne
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662490/
https://ncbi.nlm.nih.gov/pubmed/26002555
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