Tracking sub-clonal TP53 mutated tumor cells in human metastatic renal cell carcinoma

Renal Cell Carcinomas (RCCs) are heterogeneous tumors with late acquisition of TP53 abnormalities during their evolution. They harbor TP53 abnormalities in their metastases. We aimed to study TP53 gene alterations in tissue samples from primary and metastatic RCCs in 36 patients followed up over a m...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bousquet, Guilhem, Bouchtaoui, Morad El, Leboeuf, Christophe, Battistella, Maxime, Varna, Mariana, Ferreira, Irmine, Plassa, Louis-François, Hamdan, Diaddin, Bertheau, Philippe, Feugeas, Jean-Paul, Damotte, Diane, Janin, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662490/
https://ncbi.nlm.nih.gov/pubmed/26002555
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