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TP53 Status and Response to Treatment in Breast Cancers

The p53 wild-type protein plays an important role in cells as is shown by its fine regulation at different levels. Since its discovery, numerous mutations have been described. In breast cancers, p53 is mutated in almost 30% of cases, with a higher frequency in some tumor subtypes. TP53 mutation is r...

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Detalhes bibliográficos
Main Authors: Varna, Mariana, Bousquet, Guilhem, Plassa, Louis-François, Bertheau, Philippe, Janin, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114547/
https://ncbi.nlm.nih.gov/pubmed/21760703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/284584
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