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MicroRNA-106b inhibits osteoclastogenesis and osteolysis by targeting RANKL in giant cell tumor of bone

Giant cell tumor (GCT) of bone consists of three major cell types: giant cells, monocytic cells, and stromal cells. From microarray analysis, we found that miR-106b was down-regulated in GCT clinical samples and further determined by fluorescence in situ hybridization. In addition, the expression of...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Wang, Ting, Yin, Huabin, Wang, Jing, Li, Zhenxi, Wei, Haifeng, Liu, Zhi'an, Wu, Zhipeng, Yan, Wangjun, Liu, Tielong, Song, Dianwen, Yang, Xinghai, Huang, Quan, Zhou, Wang, Xiao, Jianru
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662469/
https://ncbi.nlm.nih.gov/pubmed/26053181
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