Notch Cooperates with Survivin to Maintain Stemness and to Stimulate Proliferation in Human Keratinocytes during Ageing

The Notch signaling pathway orchestrates cell fate by either inducing cell differentiation or maintaining cells in an undifferentiated state. This study aims to evaluate Notch expression and function in normal human keratinocytes. Notch1 is expressed in all epidermal layers, though to a different de...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Palazzo, Elisabetta, Morandi, Paolo, Lotti, Roberta, Saltari, Annalisa, Truzzi, Francesca, Schnebert, Sylvianne, Dumas, Marc, Marconi, Alessandra, Pincelli, Carlo
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661807/
https://ncbi.nlm.nih.gov/pubmed/26540052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms161125948
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